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Independent evidence before payment.
Neuropeptide · also: Delta sleep-inducing peptide
DSIP carries an Evidence Grade of C (Medium confidence). The strongest published evidence catalogued is human (other).
Grade C rule: At least one other human study.
The grade reflects the strength of the published evidence, not safety or efficacy. “Confidence” means how settled that grade is given the record — not how likely the compound is to work.
Human-use stop
This compound is investigational, warned or not approved for human use. A seller calling it “research only,” showing testimonials, registering a company or publishing a COA does not create an approved consumer medicine. Seller links below are market-surveillance records, not recommendations.
DSIP (delta sleep-inducing peptide) is a neuropeptide studied for sleep and stress endpoints in older, mostly small studies.
Animal and in-vitro results are shown separately and must never be read as established human outcomes.
In plain terms: there is 1 human study, but no randomised trial — the strongest test has not been done. Effects seen in smaller studies often do not hold up.
Strongest: randomised or pooled human trials.
none catalogued
Observational, open-label or small human studies.
Presence of delta-sleep-inducing peptide-like material in human milk. The Journal of clinical endocrinology and metabolism, 1984.
Preclinical animal models — not a human outcome.
Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke. Molecules (Basel, Switzerland), 2021.
Delta sleep-inducing peptide (DSIP) stimulates LH release in steroid-primed ovariectomized rats. Life sciences, 1987.
Cell / tissue studies — not a human outcome.
none catalogued
Proposed mechanism — hypothesis, not evidence of effect.
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2026.
Peptides and the blood-brain barrier. Peptides, 2015.
Delta-sleep inducing peptide entrapment in the charged macroporous matrices. Materials science & engineering. C, Materials for biological applications, 2014.
Delta sleep-inducing peptide (DSIP): a still unresolved riddle. Journal of neurochemistry, 2006.
Delta sleep-inducing peptide. European journal of anaesthesiology, 2001.
[DSIP: the sleep peptide or an unknown hypothalamic hormone?]. Zhurnal evoliutsionnoi biokhimii i fiziologii, 1994.
Delta-sleep-inducing peptide (DSIP): an update. Peptides, 1986.
Delta-sleep-inducing peptide (DSIP): a review. Neuroscience and biobehavioral reviews, 1984.
Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. Proceedings of the National Academy of Sciences of the United States of America, 1977.
On “cited by N”: citation counts (Crossref) reflect how often a paper has been referenced — a measure of academic attention, not of validity, safety, or whether a compound works. They do not affect the Evidence Grade, which is set purely by the strength of the evidence tier.
The literature is old and inconsistent; modern, well-powered replication is lacking.
Not an approved medicine in major markets. Sold only as a “research chemical”, with no established safe consumer use, dose or supply standard.
PepCred flags any vendor selling this compound to the public as a consumer-protection concern. Status reflects regulator records; see the regulatory detail below.
No FDA-approved (US) drug labelling found for this compound. A search of openFDA returned no approved product containing it as an active ingredient.
This reflects US FDA approval only — other regulators (e.g. MHRA, EMA) may differ; see the note below. Absence of an approved label is not, by itself, a safety finding, and a “research use only” label does not establish safety, legality or correct identity.
PepCred note: Not approved for human use.
These unranked records show where the name was detected. For an investigational, warned or unapproved compound, no seller, company registration, review score or COA creates an approved human-use route.
None of these is verified for human use.